Oxytocin Therapy Among Parturient Women in A University Hospital in Benin City, Nigeria
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Abstract
Background: Synthetic oxytocin is commonly used for labour management. There is no clear evidence to recommend a particular regimen of oxytocin in labour. This study was designed to document our experience with the use of oxytocin during labour and delivery with a view to improving maternal and perinatal outcome.
Methods: We conducted a retrospective study of consecutive deliveries from July to December 2019 in the Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin City, Nigeria, including all women who had oxytocin administered in the setting of labour and delivery. The data was subjected to statistical analysis with SPSS version 20.0 and GraphPad InStat 3, and P value < 0.05 was adjudged to be statistically significant.
Results: Of 1,275 women who delivered in the period studied, 620 (50.2%) had oxytocin for induction of labour, 13.4% had stimulation of uterine contractions following rupture of membranes, and 36.4% had augmentation of labour. Almost 70% of the women delivered within 8h of initiating oxytocin therapy, 3% had oxytocin beyond 12h, and about 30% of them required the maximum dose of 32mU/min. Vaginal delivery occurred in 76% of the women. We did not find any significant predictor of vaginal delivery. And no complications of oxytocin use were recorded.
Conclusion: Vaginal delivery rate is good among parturient women treated with oxytocin in labour in our hospital. With adequate monitoring and appropriate management, maternal and perinatal complications are rare.
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